Cortisone is a steroid hormone. Chemically, it is a corticosteroid closely related to corticosterone.
Production
Cortisone is one of several end products of a process called steroidogenesis.
This process starts with cholesterol which then goes through a series of reactions in the adrenal gland to produce a variety of steroid hormones.
One endproduct of this pathway is cortisol, which is then released from the adrenal gland by ACTH signaling from the anterior pituitary, which is stimulated by corticotropin-releasing hormone from the hypothalamus in the brain.
In the peripheral tissues cortisol is converted to cortisone by 11-beta-steroid dehydrogenase.
Cortisol has much greater glucocorticoid activity than cortisone and thus cortisone can be considered an inactive metabolite of cortisol.
However 11-beta-steroid dehydrogenase can catalyze the reverse reaction as well and thus cortisone is also the inactive precursor molecule of the active hormone cortisol.
Cortisone is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form, cortisol, is thus sometimes referred to as hydrocortisone.
Effects and uses
Cortisol and adrenaline are the main hormones released by the body as a reaction to stress.
They elevate blood pressure and prepare the body for a fight or flight response.
Cortisone is sometimes used as a drug to treat a variety of ailments.
It can be administered intravenously or cutaneously.
One of cortisone's effects on the body, and a potentially harmful side effect when administered clinically, is the suppression of the immune system.
This could be the explanation for the apparent correlation between high stress and sickness.
The suppression of the immune system may be important in the treatment of inflammatory conditions such as severe IgE-mediated allergies.
Cortisone is less important than a similar steroid cortisol. Cortisol is responsible for 95% of the effects of the glucocorticosteroids while cortisone is about 4 or 5%. Corticosterone is even less important.
Cortisone shots also may leave "dents" in the injection area, in some cases.
History
Cortisone was first discovered by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic.
He won the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and functions.
Please Visit http://www.healmyskin.net For More Information
Thursday, December 24, 2009
Yeast Infection Symptoms In Men and Women
Among the ailments that can really disturb any one’s life we can find, without any doubt and in the very first places, what is known as a yeast infection. This is a very resistant infection caused by fungi that suddenly start reproducing in a huge rate, overgrowing any competitor organisms and invading a part of the body.
The parts of the body that are more easily invaded by yeast are the mouth, sex organs and some areas of the skin. The basic characteristic that favors the high rate of reproduction of fungi in these areas is the moistness, warm temperature and natural existence of these zones of the body.
The main symptoms characteristic of a yeast infection are pretty varied, involving more than just a simple red skin. Among them we can find : Vaginal odor, painful sex or sexual dysfunction, white vaginal discharge, premature aging, arthritis, depression, chronic rashes, tiredness, poor memory, irritability, joint pain, PMS, feeling rundown, digestive problems, muscle aches, short attention span, hand pain, hip and knee pain, continuos headaches, acne problems, respiratory infections, memory loss, immune system weakness, skin problems, cases of impotence, intestinal gas, hand pain, hypoglycemia, menstrual pain, urinary disorders, skin lesions, shortness of breath, food allergies and even learning and memory problems.
As you can see, the contraction of a yeast infection can have serious consequences that can affect your quality of life in a number of ways. That’s why the importance of combating yeast infections since the first symptoms appear. These kind of infections by fungi are not simple to cure but they are totally curable by following the right treatment.
For a 100% natural yeast infection cure visit:
=>> http://www.askingplanet.com/Yeast-Infection-Cure
The parts of the body that are more easily invaded by yeast are the mouth, sex organs and some areas of the skin. The basic characteristic that favors the high rate of reproduction of fungi in these areas is the moistness, warm temperature and natural existence of these zones of the body.
The main symptoms characteristic of a yeast infection are pretty varied, involving more than just a simple red skin. Among them we can find : Vaginal odor, painful sex or sexual dysfunction, white vaginal discharge, premature aging, arthritis, depression, chronic rashes, tiredness, poor memory, irritability, joint pain, PMS, feeling rundown, digestive problems, muscle aches, short attention span, hand pain, hip and knee pain, continuos headaches, acne problems, respiratory infections, memory loss, immune system weakness, skin problems, cases of impotence, intestinal gas, hand pain, hypoglycemia, menstrual pain, urinary disorders, skin lesions, shortness of breath, food allergies and even learning and memory problems.
As you can see, the contraction of a yeast infection can have serious consequences that can affect your quality of life in a number of ways. That’s why the importance of combating yeast infections since the first symptoms appear. These kind of infections by fungi are not simple to cure but they are totally curable by following the right treatment.
For a 100% natural yeast infection cure visit:
=>> http://www.askingplanet.com/Yeast-Infection-Cure
The Law of Cause and Effect: Women's Health
If you continue to have the same habits towards your health, weight, diet, exercise, and fat, than you will continue to live with the same body that you have now, instead of living the ultimate healthy lifestyle that you deserve.
If you are not happy with your life, you need to change what you are doing. You need to stop what isn't working, and find something that will work. If you keep doing the same things you will get the same results. I would like to point out the reason that sometimes we need to change what we are doing if we are not happy with who, and what we are.
'Insanity is doing the same thing over and over again and expecting a different result”.
If you find something that works, keep with it. A Football team will keep running a successful play until the other team figures out a way to stop it.
Here are a few simple examples of the Law of Cause and Effect: -If you exercise, you get stronger. -If you eat too much, you’ll get fat. -If you save your money, you’ll become wealthy. -If you don't maintain your car - it breaks down. (Usually at an inconvenient time) -If you spend more than you make, you could end up being a financial slave to a credit card company, lose yourself-respect, or possibly lose your house.
The person who is likely to succeed is a person who in their spare time, takes night classes, home study classes, attends workshops, searches out information to help them achieve their personal goals, and doesn’t give up, no matter how difficult it may seem.
The person who usually fails is the person who comes home from work and spends countless hours watching television, is not motivated, and gives up too easily. They are missing a key ingredient which is a burning desire. This is not something you can purchase, it is something that you can create in yourself, just through positive self talk.
So today I am asking you to make a change in your life! If you are not healthy and happy, and you continue to do the same things that are not working than you are insane. So as Susan Powders would say “Stop The Insanity”. Make a commitment to change and develop the burning desire mindset.
Kimberly Jamieson http://www.healthypainfreeliving.com Has achieved success in living, maintaining a healthy active lifestyle. She has helped inspire and motivate thousands to achieve this life. To learn more about women’s health and wellness, overeating, weight loss, exercise, proper eating habits. Visit http://www.healthypainfreeliving.com
Kimberly Jamieson http://www.healthypainfreeliving.com Has achieved success in living, maintaining a healthy active lifestyle. She has helped inspire and motivate thousands to achieve this life. To learn more about women’s health and wellness, overeating, weight loss, exercise, proper eating habits. Visit http://www.healthypainfreeliving.com
If you are not happy with your life, you need to change what you are doing. You need to stop what isn't working, and find something that will work. If you keep doing the same things you will get the same results. I would like to point out the reason that sometimes we need to change what we are doing if we are not happy with who, and what we are.
'Insanity is doing the same thing over and over again and expecting a different result”.
If you find something that works, keep with it. A Football team will keep running a successful play until the other team figures out a way to stop it.
Here are a few simple examples of the Law of Cause and Effect: -If you exercise, you get stronger. -If you eat too much, you’ll get fat. -If you save your money, you’ll become wealthy. -If you don't maintain your car - it breaks down. (Usually at an inconvenient time) -If you spend more than you make, you could end up being a financial slave to a credit card company, lose yourself-respect, or possibly lose your house.
The person who is likely to succeed is a person who in their spare time, takes night classes, home study classes, attends workshops, searches out information to help them achieve their personal goals, and doesn’t give up, no matter how difficult it may seem.
The person who usually fails is the person who comes home from work and spends countless hours watching television, is not motivated, and gives up too easily. They are missing a key ingredient which is a burning desire. This is not something you can purchase, it is something that you can create in yourself, just through positive self talk.
So today I am asking you to make a change in your life! If you are not healthy and happy, and you continue to do the same things that are not working than you are insane. So as Susan Powders would say “Stop The Insanity”. Make a commitment to change and develop the burning desire mindset.
Kimberly Jamieson http://www.healthypainfreeliving.com Has achieved success in living, maintaining a healthy active lifestyle. She has helped inspire and motivate thousands to achieve this life. To learn more about women’s health and wellness, overeating, weight loss, exercise, proper eating habits. Visit http://www.healthypainfreeliving.com
Kimberly Jamieson http://www.healthypainfreeliving.com Has achieved success in living, maintaining a healthy active lifestyle. She has helped inspire and motivate thousands to achieve this life. To learn more about women’s health and wellness, overeating, weight loss, exercise, proper eating habits. Visit http://www.healthypainfreeliving.com
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